Publications

NecLip-FVIII

  • 1. Baru M., Carmel-Goren L., Barenholz Y., Dayan I., Ostropolets S., Slepoy I., et al. Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy. Thromb. Haemost. 93(6) (2005): 1061-1068.
  • 2. Spira J., Plyushch O.P., Andreeva T.A., Andreev Y. Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes. Blood 108(12) (2006): 3668-3673.
  • 3. Spira J, Plyushch OP, Andreeva TA, Khametova RN. Evaluation of liposomal dose in recombinant factor VIII reconstituted with pegylated liposomes for the treatment of patients with severe haemophilia A. Thromb Haemost 2008; 100: 429-34.
  • 4. Powell J.S. Liposomal approach towards the development of a longer-acting factor VIII. Haemophilia 13 (Suppl 2) (2007): 23-28.
  • 5. Powell J.S., Nugent D.J., Harrison J.A., Soni A., Luk A., Stass H. et al., Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A. J Thromb Haemost. 6(2) (2008): 277-283.
  • 6. Powell J.S. The next generation of anti-haemophilia factor, factor VIII. Long-lasting protection from spontaneous bleeding, are we there yet? Thromb Haemost. 100 (2008):365-6.

NecLip-FVIIa

  • 7. Yatuv R., Dayan I., Carmel-Goren L., Robinson M., Aviv I., Goldenberg-Furmanov M. et al., Enhancement of factor VIIa haemostatic efficacy by formulation with PEGylated liposomes. Haemophilia. 14(3) (2008): 476-83

NecLip technology and NecLip-G-CSF

  • 8. Yatuv R, Carmel-Goren L, Dayan I, Robinson M, Baru M. Binding of proteins to PEGylated liposomes and improvement of G-CSF efficacy in mobilization of hematopoietic stem cells. J Control Release 2009. 135 (2009): 44-50

Liposomal glucocorticoid

  • 9. Avnir Y, Ulmansky R, Wasserman V, Even-Chen S, Broyer M, Barenholz Y, Naparstek Y. Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: a novel approach to treating autoimmune arthritis. Arthritis Rheum. 58 (2008): 119-29.
  • 10. Cohen IR, Klareskog L. Anti-inflammatory therapy for rheumatoid arthritis? Arthritis Rheum. 58 (2008): 2-4.